Mini-review on initiatives to interfere with the propagation and clearance of alpha-synuclein in Parkinson’s disease

In this mini-review, we summarize recent findings relating to the prion-like propagation of α-synuclein (α-syn) and the development of novel therapeutic strategies to target synucleinopathy in Parkinson’s disease (PD). We link the Braak’s staging hypothesis of PD with the recent evidence from in-viv...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Daniel Kam Yin, Xu, Ying Hua, Chan, Luke Kar Man, Braidy, Nady, Mellick, George D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738184/
https://www.ncbi.nlm.nih.gov/pubmed/29270291
http://dx.doi.org/10.1186/s40035-017-0104-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738184/
https://www.ncbi.nlm.nih.gov/pubmed/29270291
http://dx.doi.org/10.1186/s40035-017-0104-6

Ejemplares similares