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Mini-review on initiatives to interfere with the propagation and clearance of alpha-synuclein in Parkinson’s disease

In this mini-review, we summarize recent findings relating to the prion-like propagation of α-synuclein (α-syn) and the development of novel therapeutic strategies to target synucleinopathy in Parkinson’s disease (PD). We link the Braak’s staging hypothesis of PD with the recent evidence from in-viv...

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Detalles Bibliográficos
Autores principales:	Chan, Daniel Kam Yin, Xu, Ying Hua, Chan, Luke Kar Man, Braidy, Nady, Mellick, George D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738184/ https://www.ncbi.nlm.nih.gov/pubmed/29270291 http://dx.doi.org/10.1186/s40035-017-0104-6

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