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Functional and cooperative stabilization of a two-metal (Ca, Zn) center in α-amylase derived from Flavobacteriaceae species

Mesophilic α-amylase from Flavobacteriaceae (FSA) is evolutionary closely related to thermophilic archaeal Pyrococcus furiosus α-amylase (PWA), but lacks the high thermostability, despite the conservation of most residues involved in the two-metal (Ca, Zn) binding center of PWA. In this study, a dis...

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Detalles Bibliográficos
Autores principales:	Yin, Huijia, Yang, Zhou, Nie, Xinyu, Li, Shannan, Sun, Xuyang, Gao, Chao, Wang, Zenghang, Zhou, Guangming, Xu, Ping, Yang, Chunyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738361/ https://www.ncbi.nlm.nih.gov/pubmed/29263337 http://dx.doi.org/10.1038/s41598-017-18085-4

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