MicroRNA-365 regulates IL-1β-induced catabolic factor expression by targeting HIF-2α in primary chondrocytes

Endothelial Per-Arnt-Sim domain protein-1/hypoxia-inducible factor-2α (EPAS-1/ HIF-2α) is a catabolic transcription factor that regulates osteoarthritis (OA)-related cartilage destruction. Here, we examined whether microRNA-365 (miR-365) affects interleukin (IL)-1β-induced expression of catabolic fa...

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Detalles Bibliográficos
Autores principales: Hwang, Hyun Sook, Park, Su Jin, Lee, Mi Hyun, Kim, Hyun Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738378/
https://www.ncbi.nlm.nih.gov/pubmed/29263346
http://dx.doi.org/10.1038/s41598-017-18059-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738378/
https://www.ncbi.nlm.nih.gov/pubmed/29263346
http://dx.doi.org/10.1038/s41598-017-18059-6

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