EGCG-mediated Protection of the Membrane Disruption and Cytotoxicity Caused by the ‘Active Oligomer’ of α-Synuclein

(−)-Epigallocatechin gallate (EGCG), the major component of green tea, has been re-evaluated with α-synuclein (αS), a pathological constituent of Parkinson’s disease, to elaborate its therapeutic value. EGCG has been demonstrated to not only induce the off-pathway ‘compact’ oligomers of αS as sugges...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jee Eun, Rhoo, Kun Yil, Lee, Soonkoo, Lee, Jong Tak, Park, Jae Hyung, Bhak, Ghibom, Paik, Seung R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738379/
https://www.ncbi.nlm.nih.gov/pubmed/29263416
http://dx.doi.org/10.1038/s41598-017-18349-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738379/
https://www.ncbi.nlm.nih.gov/pubmed/29263416
http://dx.doi.org/10.1038/s41598-017-18349-z

Ejemplares similares