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EGCG-mediated Protection of the Membrane Disruption and Cytotoxicity Caused by the ‘Active Oligomer’ of α-Synuclein
(−)-Epigallocatechin gallate (EGCG), the major component of green tea, has been re-evaluated with α-synuclein (αS), a pathological constituent of Parkinson’s disease, to elaborate its therapeutic value. EGCG has been demonstrated to not only induce the off-pathway ‘compact’ oligomers of αS as sugges...
Autores principales: | Yang, Jee Eun, Rhoo, Kun Yil, Lee, Soonkoo, Lee, Jong Tak, Park, Jae Hyung, Bhak, Ghibom, Paik, Seung R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738379/ https://www.ncbi.nlm.nih.gov/pubmed/29263416 http://dx.doi.org/10.1038/s41598-017-18349-z |
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