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Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment
Macrophages are potent immune cells with well-established roles in the response to stress, injury, infection and inflammation. The classically activated macrophages (M1) are induced by lipopolysaccharide (LPS) and express a wide range of pro-inflammatory genes. M2 macrophages are induced by T helper...
Autores principales: | Moraes, Leonardo A., Kar, Shreya, Foo, Sok Lin, Gu, Tong, Toh, Yi Qian, Ampomah, Patrick B., Sachaphibulkij, Karishma, Yap, Gracemary, Zharkova, Olga, Lukman, Hakim M., Fairhurst, Anna-Marie, Kumar, Alan Prem, Lim, Lina H. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738423/ https://www.ncbi.nlm.nih.gov/pubmed/29263330 http://dx.doi.org/10.1038/s41598-017-17622-5 |
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