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The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission

Dopamine neurotransmission is highly dysregulated by the psychostimulant methamphetamine, a substrate for the dopamine transporter (DAT). Through interactions with DAT, methamphetamine increases extracellular dopamine levels in the brain, leading to its rewarding and addictive properties. Methamphet...

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Detalles Bibliográficos
Autores principales: Sambo, Danielle O., Lin, Min, Owens, Anthony, Lebowitz, Joseph J., Richardson, Ben, Jagnarine, Darin A., Shetty, Madhur, Rodriquez, Meghan, Alonge, Taiwo, Ali, Mishaal, Katz, Jonathan, Yan, Long, Febo, Marcelo, Henry, L. Keith, Bruijnzeel, Adriaan W., Daws, Lynette, Khoshbouei, Habibeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738444/
https://www.ncbi.nlm.nih.gov/pubmed/29263318
http://dx.doi.org/10.1038/s41467-017-02087-x