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Post-Transcriptional Regulation of Hepatic DDAH1 with TNF Blockade Leads to Improved eNOS Function and Reduced Portal Pressure In Cirrhotic Rats

Portal hypertension (PH) is a major cause of morbidity and mortality in chronic liver disease. Infection and inflammation play a role in potentiating PH and pro-inflammatory cytokines, including TNF, are associated with severity of PH. In this study, cirrhotic bile duct ligated (BDL) rats with PH we...

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Detalles Bibliográficos
Autores principales:	Balasubramanian, V., Mehta, G., Jones, H., Sharma, V., Davies, N. A., Jalan, R., Mookerjee, R. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738445/ https://www.ncbi.nlm.nih.gov/pubmed/29263339 http://dx.doi.org/10.1038/s41598-017-18094-3

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