Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model

BACKGROUND & AIMS: The incidence of nonalcoholic steatohepatitis (NASH) is increasing. The pathophysiological mechanisms of NASH and the sequence of events leading to hepatic fibrosis are incompletely understood. The aim of this study was to gain insight into the dynamics of key molecular proces...

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Detalles Bibliográficos
Autores principales: van Koppen, Arianne, Verschuren, Lars, van den Hoek, Anita M., Verheij, Joanne, Morrison, Martine C., Li, Kelvin, Nagabukuro, Hiroshi, Costessi, Adalberto, Caspers, Martien P.M., van den Broek, Tim J., Sagartz, John, Kluft, Cornelis, Beysen, Carine, Emson, Claire, van Gool, Alain J., Goldschmeding, Roel, Stoop, Reinout, Bobeldijk-Pastorova, Ivana, Turner, Scott M., Hanauer, Guido, Hanemaaijer, Roeland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738456/
https://www.ncbi.nlm.nih.gov/pubmed/29276754
http://dx.doi.org/10.1016/j.jcmgh.2017.10.001

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