Cargando…

Indian Hedgehog Suppresses a Stromal Cell–Driven Intestinal Immune Response

BACKGROUND & AIMS: Upon intestinal epithelial damage a complex wound healing response is initiated to restore epithelial integrity and defend against pathogenic invasion. Epithelium-derived Indian Hedgehog (Ihh) functions as a critical sensor in this process. Signaling occurs in a paracrine mann...

Descripción completa

Detalles Bibliográficos
Autores principales:	Westendorp, B. Florien, Büller, Nikè V.J.A., Karpus, Olga N., van Dop, Willemijn A., Koster, Jan, Versteeg, Rogier, Koelink, Pim J., Snel, Clinton Y., Meisner, Sander, Roelofs, Joris J.T.H., Uhmann, Anja, Ver Loren van Themaat, Emiel, Heijmans, Jarom, Hahn, Heidi, Muncan, Vanesa, Wildenberg, Manon E., van den Brink, Gijs R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738458/ https://www.ncbi.nlm.nih.gov/pubmed/29276753 http://dx.doi.org/10.1016/j.jcmgh.2017.08.004

Ejemplares similares

Rage mediated DAMP signaling in intestinal tumorigenesis
por: Heijmans, Jarom, et al.
Publicado: (2012)

Blimp1 regulates the transition of neonatal to adult intestinal epithelium
por: Muncan, Vanesa, et al.
Publicado: (2011)

ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair
por: Meijer, Bartolomeus J., et al.
Publicado: (2020)

A Novel Organoid Model of Damage and Repair Identifies HNF4α as a Critical Regulator of Intestinal Epithelial Regeneration
por: Montenegro-Miranda, Paula S., et al.
Publicado: (2020)

Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2
por: Meijer, Bartolomeus J., et al.
Publicado: (2021)

Expression of UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell proliferation and stemness by activating PERK signaling
por: Spaan, Claudia N., et al.
Publicado: (2019)

Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis
por: Spaan, Claudia N, et al.
Publicado: (2023)

Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis
por: van der Meer, Jonathan H. M., et al.
Publicado: (2021)

Colorectal tumor prevention by the progestin medroxyprogesterone acetate is critically dependent on postmenopausal status
por: Meijer, Bartolomeus J., et al.
Publicado: (2018)

Early Life Antibiotics Influence In Vivo and In Vitro Mouse Intestinal Epithelium Maturation and Functioning
por: Garcia, Tânia Martins, et al.
Publicado: (2021)

Mouse fetal intestinal organoids: new model to study epithelial maturation from suckling to weaning
por: Navis, Marit, et al.
Publicado: (2018)

Beneficial Effect of Mildly Pasteurized Whey Protein on Intestinal Integrity and Innate Defense in Preterm and Near-Term Piglets
por: Navis, Marit, et al.
Publicado: (2020)

The GI–CDF module of Arabidopsis affects freezing tolerance and growth as well as flowering
por: Fornara, Fabio, et al.
Publicado: (2015)

Intestinal Tumorigenesis Is Not Affected by Progesterone Signaling in Rodent Models
por: Heijmans, Jarom, et al.
Publicado: (2011)

Correction: Intestinal Tumorigenesis Is Not Affected by Progesterone Signaling in Rodent Models
por: Heijmans, Jarom, et al.
Publicado: (2013)

Genetic Dissection of a Prevalent Plasmid-Encoded Conjugation System in Lactococcus lactis
por: Ortiz Charneco, Guillermo, et al.
Publicado: (2021)

Altered Gut Structure and Anti-Bacterial Defense in Adult Mice Treated with Antibiotics during Early Life
por: Martins Garcia, Tânia, et al.
Publicado: (2022)

Mitochondrial 2,4-dienoyl-CoA Reductase Deficiency in Mice Results in Severe Hypoglycemia with Stress Intolerance and Unimpaired Ketogenesis
por: Miinalainen, Ilkka J., et al.
Publicado: (2009)

Erratum: Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth
por: Gerling, Marco, et al.
Publicado: (2016)

F205. OLFACTORY IDENTIFICATION IN 7-YEAR OLD CHILDREN AT FAMILIAL RISK TO DEVELOP SCHIZOPHRENIA
por: van Themaat, Anna Hester Ver Loren, et al.
Publicado: (2018)

P1440: ASSESSING ADHERENCE TO EMERGENCY DEPARTMENT PROTOCOLS FOR SICKLE CELL DISEASE: IMPLICATIONS FOR QUALITY OF CARE
por: van Tuijn, Charlotte, et al.
Publicado: (2023)

Classification-based comparison of pre-processing methods for interpretation of mass spectrometry generated clinical datasets
por: Wegdam, Wouter, et al.
Publicado: (2009)

Sequential Delivery of Host-Induced Virulence Effectors by Appressoria and Intracellular Hyphae of the Phytopathogen Colletotrichum higginsianum
por: Kleemann, Jochen, et al.
Publicado: (2012)

Correction: Sequential Delivery of Host-Induced Virulence Effectors by Appressoria and Intracellular Hyphae of the Phytopathogen Colletotrichum higginsianum
por: Kleemann, Jochen, et al.
Publicado: (2012)

Thiopurines correct the effects of autophagy impairment on intestinal healing – a potential role for ARHGAP18/RhoA
por: Prins, Marileen M. C., et al.
Publicado: (2021)

Incidence of Sars-COV-2 Infection in Sickle Cell Patients Presenting with a Painful Crisis, a 12 Month Prospective Cohort Study
por: Konté, Kadère, et al.
Publicado: (2021)

Incidence of SARS‐COV‐2 infection in sickle cell patients presenting with a painful crisis: A 12‐month prospective cohort study
por: Konté, Kadère, et al.
Publicado: (2021)

Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study
por: Schouten, Marcel, et al.
Publicado: (2010)

Protease-activated receptor-1 impairs host defense in murine pneumococcal pneumonia: a controlled laboratory study
por: Schouten, Marcel, et al.
Publicado: (2012)

The transcriptomic signature of fasting murine liver
por: Sokolović, Milka, et al.
Publicado: (2008)

Sirolimus for the treatment of polyposis of the rectal remnant and ileal pouch in four patients with familial adenomatous polyposis: a pilot study
por: Roos, Victorine H, et al.
Publicado: (2020)

Monocyte TREM-1 Levels Associate With Anti-TNF Responsiveness in IBD Through Autophagy and Fcγ-Receptor Signaling Pathways
por: Prins, Marileen M., et al.
Publicado: (2021)

The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer
por: Kodach, Liudmila L., et al.
Publicado: (2010)

Cause-specific Mortality in a Population-based Cohort of 9799 Women Treated for Ductal Carcinoma In Situ
por: Elshof, Lotte E., et al.
Publicado: (2018)

Structure and evolution of barley powdery mildew effector candidates
por: Pedersen, Carsten, et al.
Publicado: (2012)

Benzimidazoles Promote Anti-TNF Mediated Induction of Regulatory Macrophages and Enhance Therapeutic Efficacy in a Murine Model
por: Wildenberg, Manon E, et al.
Publicado: (2017)

Key Components of Different Plant Defense Pathways Are Dispensable for Powdery Mildew Resistance of the Arabidopsis mlo2 mlo6 mlo12 Triple Mutant
por: Kuhn, Hannah, et al.
Publicado: (2017)

Hybrid operation technique for incisional hernia repair: a systematic review and meta-analysis of intra- and postoperative complications
por: Van den Dop, L. Matthijs, et al.
Publicado: (2021)

Limited role for ASC and NLRP3 during in vivo Salmonella Typhimurium infection
por: De Jong, Hanna K, et al.
Publicado: (2014)

Development of Reliable, Valid and Responsive Scoring Systems for Endoscopy and Histology in Animal Models for Inflammatory Bowel Disease
por: Koelink, Pim J, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pdatqu0knubjid8usai5rm1ei3