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Risk factors for ectopic pregnancy in Germany: a retrospective study of 100,197 patients
Aim: The goal of this study was to identify potential risk factors for ectopic pregnancy in women followed in German gynecological practices. Methods: The present study included pregnant women diagnosed with ectopic pregnancy and pregnant women without ectopic pregnancy followed in 262 gynecological...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
German Medical Science GMS Publishing House
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738501/ https://www.ncbi.nlm.nih.gov/pubmed/29308062 http://dx.doi.org/10.3205/000260 |
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author | Jacob, Louis Kalder, Matthias Kostev, Karel |
author_facet | Jacob, Louis Kalder, Matthias Kostev, Karel |
author_sort | Jacob, Louis |
collection | PubMed |
description | Aim: The goal of this study was to identify potential risk factors for ectopic pregnancy in women followed in German gynecological practices. Methods: The present study included pregnant women diagnosed with ectopic pregnancy and pregnant women without ectopic pregnancy followed in 262 gynecological practices between January 2012 and December 2016. The effects of demographic and clinical variables on the risk of developing ectopic pregnancy were estimated using a multivariate logistic regression model. Results: This study included 3,003 women with ectopic pregnancy and 97,194 women without ectopic pregnancy. The mean age was 31.4 years (SD=5.9 years) in ectopic pregnancy patients and 31.1 years (SD=5.6 years) in non-ectopic pregnancy patients. Women aged 36–40 (OR=1.12) and 41–45 years (OR=1.46) were at a higher risk of ectopic pregnancy than women aged 31–35 years. Prior ectopic pregnancy was strongly associated with a risk of recurring ectopic pregnancy (OR=8.17). Prior genital surgery (OR=2.67), endometriosis (OR=1.51), and eight other gynecological diseases were also positively associated with ectopic pregnancy (ORs ranging from 1.19 to 2.06). Finally, there was a 1.80-fold increase in women previously diagnosed with psychiatric disorders. Conclusions: Prior ectopic pregnancy and prior genital surgery were strongly associated with ectopic pregnancy in women followed in German gynecological practices. Psychiatric diseases had an additional impact on the risk of ectopic pregnancy. |
format | Online Article Text |
id | pubmed-5738501 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | German Medical Science GMS Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-57385012018-01-05 Risk factors for ectopic pregnancy in Germany: a retrospective study of 100,197 patients Jacob, Louis Kalder, Matthias Kostev, Karel Ger Med Sci Article Aim: The goal of this study was to identify potential risk factors for ectopic pregnancy in women followed in German gynecological practices. Methods: The present study included pregnant women diagnosed with ectopic pregnancy and pregnant women without ectopic pregnancy followed in 262 gynecological practices between January 2012 and December 2016. The effects of demographic and clinical variables on the risk of developing ectopic pregnancy were estimated using a multivariate logistic regression model. Results: This study included 3,003 women with ectopic pregnancy and 97,194 women without ectopic pregnancy. The mean age was 31.4 years (SD=5.9 years) in ectopic pregnancy patients and 31.1 years (SD=5.6 years) in non-ectopic pregnancy patients. Women aged 36–40 (OR=1.12) and 41–45 years (OR=1.46) were at a higher risk of ectopic pregnancy than women aged 31–35 years. Prior ectopic pregnancy was strongly associated with a risk of recurring ectopic pregnancy (OR=8.17). Prior genital surgery (OR=2.67), endometriosis (OR=1.51), and eight other gynecological diseases were also positively associated with ectopic pregnancy (ORs ranging from 1.19 to 2.06). Finally, there was a 1.80-fold increase in women previously diagnosed with psychiatric disorders. Conclusions: Prior ectopic pregnancy and prior genital surgery were strongly associated with ectopic pregnancy in women followed in German gynecological practices. Psychiatric diseases had an additional impact on the risk of ectopic pregnancy. German Medical Science GMS Publishing House 2017-12-19 /pmc/articles/PMC5738501/ /pubmed/29308062 http://dx.doi.org/10.3205/000260 Text en Copyright © 2017 Jacob et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Jacob, Louis Kalder, Matthias Kostev, Karel Risk factors for ectopic pregnancy in Germany: a retrospective study of 100,197 patients |
title | Risk factors for ectopic pregnancy in Germany: a retrospective study of 100,197 patients |
title_full | Risk factors for ectopic pregnancy in Germany: a retrospective study of 100,197 patients |
title_fullStr | Risk factors for ectopic pregnancy in Germany: a retrospective study of 100,197 patients |
title_full_unstemmed | Risk factors for ectopic pregnancy in Germany: a retrospective study of 100,197 patients |
title_short | Risk factors for ectopic pregnancy in Germany: a retrospective study of 100,197 patients |
title_sort | risk factors for ectopic pregnancy in germany: a retrospective study of 100,197 patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738501/ https://www.ncbi.nlm.nih.gov/pubmed/29308062 http://dx.doi.org/10.3205/000260 |
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