Tumour-associated neutrophils and loss of epithelial PTEN can promote corticosteroid-insensitive MMP-9 expression in the chronically inflamed lung microenvironment

Matrix metalloproteinase-9 (MMP-9) is increased in a number of pathological lung conditions, where the proteinase contributes to deleterious remodelling of the airways. While both lung cancer and COPD are associated with increased MMP-9 expression, the cellular and molecular drivers of MMP-9 remain...

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Detalles Bibliográficos
Autores principales: Vannitamby, Amanda, Seow, Huei Jiunn, Anderson, Gary, Vlahos, Ross, Thompson, Michelle, Steinfort, Daniel, Irving, Louis B, Bozinovski, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738540/
https://www.ncbi.nlm.nih.gov/pubmed/28202627
http://dx.doi.org/10.1136/thoraxjnl-2016-209389

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