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Design, Synthesis, and Cytotoxicity Evaluation of Novel Griseofulvin Analogues with Improved Water Solubility

Griseofulvin 1 is an important antifungal agent that has recently received attention due to its antiproliferative activity in mammalian cancer cells. Study of SAR of some griseofulvin analogues has led to the identification of 2′-benzyloxy griseofulvin 3, a more potent analogue which retards tumor g...

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Detalles Bibliográficos
Autores principales: Hamdy, Ahmed K., Sheha, Mahmoud M., Abdel-Hafez, Atef A., Shouman, Samia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738580/
https://www.ncbi.nlm.nih.gov/pubmed/29362676
http://dx.doi.org/10.1155/2017/7386125

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