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Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
Euphorbia umbellata (Pax) Bruyns is an easily cultivated shrub, with occurrence in the tropical regions of the American and African continents. Chemical studies have revealed that the latex of this plant is rich in terpene compounds, which are highly toxic to snails Biomphalaria glabrata (Basommatop...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Instituto de Medicina Tropical
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738770/ https://www.ncbi.nlm.nih.gov/pubmed/29267593 http://dx.doi.org/10.1590/S1678-9946201759085 |
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author | Pereira, Luciana Patrícia Lima Alves Dias, Clarice Noleto Miranda, Milena Valadar Firmo, Wellyson da Cunha Araújo Rosa, Carliane dos Santos Santos, Priscila Freitas Brito, Maria Cristiane Aranha Araruna, Fernanda Oliveira Sousa Araruna, Felipe Bastos Silva-Souza, Nêuton Coutinho, Denise Fernandes |
author_facet | Pereira, Luciana Patrícia Lima Alves Dias, Clarice Noleto Miranda, Milena Valadar Firmo, Wellyson da Cunha Araújo Rosa, Carliane dos Santos Santos, Priscila Freitas Brito, Maria Cristiane Aranha Araruna, Fernanda Oliveira Sousa Araruna, Felipe Bastos Silva-Souza, Nêuton Coutinho, Denise Fernandes |
author_sort | Pereira, Luciana Patrícia Lima Alves |
collection | PubMed |
description | Euphorbia umbellata (Pax) Bruyns is an easily cultivated shrub, with occurrence in the tropical regions of the American and African continents. Chemical studies have revealed that the latex of this plant is rich in terpene compounds, which are highly toxic to snails Biomphalaria glabrata (Basommatophora: Planorbidae). The aim of this study was to evaluate the chemical composition and molluscicidal activity of the latex produced by E. umbellata, as well as the safety of its application in aquatic environments. The concentration of latex that killed 90% of the exposed snails after 24 h exposure (LC(90)) was 3.69 mg/L. Toxicity bioassays using Danio rerio (zebrafish) revealed that these animals were less susceptible to latex than planorbids. However, it is important to perform other toxicity tests to ensure the feasibility of using latex to control populations of mollusks that contribute to schistosomiasis transmission. A phytochemical screening performed with the E. umbellata latex identified the triterpenoid and coumarin class. Further studies are warranted to isolate, identify, and test the active compounds of E. umbellata latex in B. glabrata. |
format | Online Article Text |
id | pubmed-5738770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Instituto de Medicina Tropical |
record_format | MEDLINE/PubMed |
spelling | pubmed-57387702018-01-02 Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail Pereira, Luciana Patrícia Lima Alves Dias, Clarice Noleto Miranda, Milena Valadar Firmo, Wellyson da Cunha Araújo Rosa, Carliane dos Santos Santos, Priscila Freitas Brito, Maria Cristiane Aranha Araruna, Fernanda Oliveira Sousa Araruna, Felipe Bastos Silva-Souza, Nêuton Coutinho, Denise Fernandes Rev Inst Med Trop Sao Paulo Brief Communication Euphorbia umbellata (Pax) Bruyns is an easily cultivated shrub, with occurrence in the tropical regions of the American and African continents. Chemical studies have revealed that the latex of this plant is rich in terpene compounds, which are highly toxic to snails Biomphalaria glabrata (Basommatophora: Planorbidae). The aim of this study was to evaluate the chemical composition and molluscicidal activity of the latex produced by E. umbellata, as well as the safety of its application in aquatic environments. The concentration of latex that killed 90% of the exposed snails after 24 h exposure (LC(90)) was 3.69 mg/L. Toxicity bioassays using Danio rerio (zebrafish) revealed that these animals were less susceptible to latex than planorbids. However, it is important to perform other toxicity tests to ensure the feasibility of using latex to control populations of mollusks that contribute to schistosomiasis transmission. A phytochemical screening performed with the E. umbellata latex identified the triterpenoid and coumarin class. Further studies are warranted to isolate, identify, and test the active compounds of E. umbellata latex in B. glabrata. Instituto de Medicina Tropical 2017-12-21 /pmc/articles/PMC5738770/ /pubmed/29267593 http://dx.doi.org/10.1590/S1678-9946201759085 Text en https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Communication Pereira, Luciana Patrícia Lima Alves Dias, Clarice Noleto Miranda, Milena Valadar Firmo, Wellyson da Cunha Araújo Rosa, Carliane dos Santos Santos, Priscila Freitas Brito, Maria Cristiane Aranha Araruna, Fernanda Oliveira Sousa Araruna, Felipe Bastos Silva-Souza, Nêuton Coutinho, Denise Fernandes Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail |
title | Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail |
title_full | Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail |
title_fullStr | Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail |
title_full_unstemmed | Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail |
title_short | Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail |
title_sort | molluscicidal effect of euphorbia umbellata (pax) bruyns latex on biomphalaria glabrata, schistosoma mansoni host snail |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738770/ https://www.ncbi.nlm.nih.gov/pubmed/29267593 http://dx.doi.org/10.1590/S1678-9946201759085 |
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