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Application of nanostructured lipid carriers: the prolonged protective effects for sesamol in in vitro and in vivo models of ischemic stroke via activation of PI3K signalling pathway
BACKGROUND: Treatment of the ischemic stroke has remained a major healthcare challenge. The phenolic compound, sesamol, has shown promising antioxidant and neuroprotective effects, however, fast clearance may negatively affect its efficiency. This, prompted us to incorporate sesamol into the nanostr...
Autores principales: | Hassanzadeh, Parichehr, Atyabi, Fatemeh, Dinarvand, Rassoul, Dehpour, Ahmad-Reza, Azhdarzadeh, Morteza, Dinarvand, Meshkat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738862/ https://www.ncbi.nlm.nih.gov/pubmed/29262855 http://dx.doi.org/10.1186/s40199-017-0191-z |
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