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Predicting DNA Hybridization Kinetics from Sequence

Hybridization is a key molecular process in biology and biotechnology, but to date there is no predictive model for accurately determining hybridization rate constants based on sequence information. Here we report a weighted neighbor voting (WNV) prediction algorithm, in which the hybridization rate...

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Detalles Bibliográficos
Autores principales: Zhang, Jinny X., Fang, John Z., Duan, Wei, Wu, Lucia R., Zhang, Angela W., Dalchau, Neil, Yordanov, Boyan, Petersen, Rasmus, Phillips, Andrew, Zhang, David Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739081/
https://www.ncbi.nlm.nih.gov/pubmed/29256499
http://dx.doi.org/10.1038/nchem.2877