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Evaluation of Antitumor Activity of Long-Circulating and pH-Sensitive Liposomes Containing Ursolic Acid in Animal Models of Breast Tumor and Gliosarcoma
Background. Ursolic acid (UA) is a triterpene found in different plant species, possessing antitumor activity, which may be a result of its antiangiogenic effect. However, UA has low water solubility, which limits its use because the bioavailability is impaired. To overcome this inconvenience, we de...
Autores principales: | Rocha, Talita Guieiro Ribeiro, Lopes, Sávia Caldeira de Araújo, Cassali, Geovani Dantas, Ferreira, Ênio, Veloso, Emerson Soares, Leite, Elaine Amaral, Braga, Fernão Castro, Ferreira, Lucas Antônio Miranda, Balvay, Daniel, Garofalakis, Anikitos, Oliveira, Mônica Cristina, Tavitian, Bertrand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739155/ https://www.ncbi.nlm.nih.gov/pubmed/27130721 http://dx.doi.org/10.1177/1534735416628273 |
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