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Epithelial contribution to the profibrotic stiff microenvironment and myofibroblast population in lung fibrosis

The contribution of epithelial-to-mesenchymal transition (EMT) to the profibrotic stiff microenvironment and myofibroblast accumulation in pulmonary fibrosis remains unclear. We examined EMT-competent lung epithelial cells and lung fibroblasts from control (fibrosis-free) donors or patients with idi...

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Detalles Bibliográficos
Autores principales: Gabasa, Marta, Duch, Paula, Jorba, Ignasi, Giménez, Alícia, Lugo, Roberto, Pavelescu, Irina, Rodríguez-Pascual, Fernando, Molina-Molina, Maria, Xaubet, Antoni, Pereda, Javier, Alcaraz, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739292/
https://www.ncbi.nlm.nih.gov/pubmed/29046395
http://dx.doi.org/10.1091/mbc.E17-01-0026