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Ovarian carcinoma glyco-antigen targeted by human IgM antibody

Epithelial Ovarian Cancer (EOC) cells expression of a novel carbohydrate antigen was defined using a human VH4-34 encoded IgM monoclonal antibody (mAb216). MAb216 binds to a poly N-acetyllactosamine epitope expressed on B cells and kills normal and malignant B cells in vitro and in vivo. EOC patient...

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Detalles Bibliográficos
Autores principales:	Chen, Yi, Bieber, Marcia M., Bhat, Neelima M., Teng, Nelson N. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739388/ https://www.ncbi.nlm.nih.gov/pubmed/29267289 http://dx.doi.org/10.1371/journal.pone.0187222

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