Metabolomic profiling and stable isotope labelling of Trichomonas vaginalis and Tritrichomonas foetus reveal major differences in amino acid metabolism including the production of 2-hydroxyisocaproic acid, cystathionine and S-methylcysteine

Trichomonas vaginalis and Tritrichomonas foetus are pathogens that parasitise, respectively, human and bovine urogenital tracts causing disease. Using LC-MS, reference metabolomic profiles were obtained for both species and stable isotope labelling with D-[U-(13)C6] glucose was used to analyse centr...

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Detalles Bibliográficos
Autores principales: Westrop, Gareth D., Wang, Lijie, Blackburn, Gavin J., Zhang, Tong, Zheng, Liang, Watson, David G., Coombs, Graham H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739422/
https://www.ncbi.nlm.nih.gov/pubmed/29267346
http://dx.doi.org/10.1371/journal.pone.0189072

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