2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice

Excessive levels of reactive oxygen species (ROS) and impaired Ca(2+) homeostasis play central roles in the development of multiple cardiac pathologies, including cell death during ischemia-reperfusion (I/R) injury. In several organs, treatment with 2-aminoethoxydiphenyl borate (2-APB) was shown to...

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Detalles Bibliográficos
Autores principales: Morihara, Hirofumi, Obana, Masanori, Tanaka, Shota, Kawakatsu, Ikki, Tsuchiyama, Daisuke, Mori, Shota, Suizu, Hiroshi, Ishida, Akiko, Kimura, Rumi, Tsuchimochi, Izuru, Maeda, Makiko, Yoshimitsu, Takehiko, Fujio, Yasushi, Nakayama, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739451/
https://www.ncbi.nlm.nih.gov/pubmed/29267336
http://dx.doi.org/10.1371/journal.pone.0189948

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