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Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer
Clinical application of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based cancer therapeutics has not reached optimal potencies in part due to inadequate drug stability and inefficiencies in cancer-selective drug delivery. As such, innovative strategies regarding drug design and...
Autores principales: | Kuroki, Lindsay M., Jin, Xingjian, Dmitriev, Igor P., Kashentseva, Elena A., Powell, Matthew A., Mutch, David G., Dietz, Allan B., Curiel, David T., Hawkins, William G., Spitzer, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739501/ https://www.ncbi.nlm.nih.gov/pubmed/29267342 http://dx.doi.org/10.1371/journal.pone.0190125 |
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