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Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer

Clinical application of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based cancer therapeutics has not reached optimal potencies in part due to inadequate drug stability and inefficiencies in cancer-selective drug delivery. As such, innovative strategies regarding drug design and...

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Detalles Bibliográficos
Autores principales: Kuroki, Lindsay M., Jin, Xingjian, Dmitriev, Igor P., Kashentseva, Elena A., Powell, Matthew A., Mutch, David G., Dietz, Allan B., Curiel, David T., Hawkins, William G., Spitzer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739501/
https://www.ncbi.nlm.nih.gov/pubmed/29267342
http://dx.doi.org/10.1371/journal.pone.0190125

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