Interleukin-21 combined with PD-1 or CTLA-4 blockade enhances antitumor immunity in mouse tumor models

Recent advances in cancer treatment with checkpoint blockade of receptors such as CTLA-4 and PD-1 have demonstrated that combinations of agents with complementary immunomodulatory effects have the potential to enhance antitumor activity as compared to single agents. We investigated the efficacy of i...

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Detalles Bibliográficos
Autores principales: Lewis, Katherine E., Selby, Mark J., Masters, Gregg, Valle, Jose, Dito, Gennaro, Curtis, Wendy R., Garcia, Richard, Mink, Kathy A., Waggie, Kimberly S., Holdren, Matthew S., Grosso, Joseph F., Korman, Alan J., Jure-Kunkel, Maria, Dillon, Stacey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739581/
https://www.ncbi.nlm.nih.gov/pubmed/29296539
http://dx.doi.org/10.1080/2162402X.2017.1377873

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