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Dietary polyphenols influence antimetabolite agents: methotrexate, 6-mercaptopurine and 5-fluorouracil in leukemia cell lines

Polyphenols have been previously shown to sensitize leukemia cell lines to topoisomerase inhibitors. Here, we assess the effects of five polyphenols when used alone and in combination with antimetabolites: methotrexate, 6-mercaptopurine and 5-fluorouracil; in lymphoid and myeloid leukemia cells line...

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Detalles Bibliográficos
Autores principales: Mahbub, Amani, Le Maitre, Christine, Haywood-Small, Sarah, Cross, Neil, Jordan-Mahy, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739607/
https://www.ncbi.nlm.nih.gov/pubmed/29285220
http://dx.doi.org/10.18632/oncotarget.20501