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Roscovitine strongly enhances the effect of olaparib on radiosensitivity for HPV neg. but not for HPV pos. HNSCC cell lines

At present, advanced stage human Papillomavirus (HPV) negative and positive head and neck squamous cell carcinoma (HNSCC) are treated by intense multimodal therapy that includes radiochemotherapy, which are associated with relevant side effects. Patients with HPV positive tumors possess a far better...

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Detalles Bibliográficos
Autores principales:	Ziemann, Frank, Seltzsam, Steve, Dreffke, Kristin, Preising, Stefanie, Arenz, Andrea, Subtil, Florentine S.B., Rieckmann, Thorsten, Engenhart-Cabillic, Rita, Dikomey, Ekkehard, Wittig, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739629/ https://www.ncbi.nlm.nih.gov/pubmed/29285242 http://dx.doi.org/10.18632/oncotarget.22005

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