Metformin alleviates nickel-induced autophagy and apoptosis via inhibition of hexokinase-2, activating lipocalin-2, in human bronchial epithelial cells

Autophagy is an intracellular recycling and degradation process for regulating tumor progression, survival and drug resistance. Nickel compounds have been identified as human carcinogens. However, the role of nickel-induced autophagy in lung carcinogenesis has not yet been fully elucidated. In this...

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Detalles Bibliográficos
Autores principales: Kang, Yu-Ting, Hsu, Wen-Cheng, Wu, Chih-Hsien, Hsin, I-Lun, Wu, Pei-Ru, Yeh, Kun-Tu, Ko, Jiunn-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739657/
https://www.ncbi.nlm.nih.gov/pubmed/29285270
http://dx.doi.org/10.18632/oncotarget.22317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739657/
https://www.ncbi.nlm.nih.gov/pubmed/29285270
http://dx.doi.org/10.18632/oncotarget.22317

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