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Activation of Nrf2 by MIND4-17 protects osteoblasts from hydrogen peroxide-induced oxidative stress

MIND4-17 is a recently developed NF-E2-related factor 2 (Nrf2) activator, which uniquely causes Nrf2 disassociation from Keap1. Here, we showed that pretreatment with MIND4-17 significantly inhibited hydrogen peroxide (H(2)O(2))-induced viability reduction of primary osteoblasts and OB-6 osteoblasti...

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Detalles Bibliográficos
Autores principales: Guo, Shiguang, Fei, Hao-Dong, Ji, Feng, Chen, Feng-Li, Xie, Yue, Wang, Shou-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739668/
https://www.ncbi.nlm.nih.gov/pubmed/29285281
http://dx.doi.org/10.18632/oncotarget.22360