Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway

Ubiquitin-specific protease 18 (USP18) as a negative regulator of the Jak/STAT signaling pathway plays an important role in the host innate immune response. USP18 has been shown to bind to the type I interferon receptor subunit 2 (IFNAR2) to down-regulate the Jak/STAT signaling. In this study, we sh...

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Detalles Bibliográficos
Autores principales: Jiao, Baihai, Shi, Xuezhen, Chen, Yanzhao, Ye, Haiyan, Yao, Min, Hong, Wenxu, Li, Shilin, Duan, Xiaoqiong, Li, Yujia, Wang, Yancui, Chen, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739690/
https://www.ncbi.nlm.nih.gov/pubmed/29285303
http://dx.doi.org/10.18632/oncotarget.22510

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