Elevated CEA is associated with worse survival in recurrent rectal cancer

This study investigated the prognostic impact of serum carcinoembryonic antigen (CEA) level in recurrent rectal cancer. We reviewed 745 patients who developed recurrence after curative treatment for rectal cancer between January 2000 and December 2012. Multivariate analyses for survival revealed tha...

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Autores principales: Cho, Won Kyung, Choi, Doo Ho, Park, Hee Chul, Park, Won, Yu, Jeong Il, Park, Young Suk, Park, Joon Oh, Lim, Ho Yeong, Kang, Won Ki, Kim, Hee Cheol, Cho, Yong Beom, Yun, Seong Hyeon, Lee, Woo Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739691/
https://www.ncbi.nlm.nih.gov/pubmed/29285304
http://dx.doi.org/10.18632/oncotarget.22511
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author Cho, Won Kyung
Choi, Doo Ho
Park, Hee Chul
Park, Won
Yu, Jeong Il
Park, Young Suk
Park, Joon Oh
Lim, Ho Yeong
Kang, Won Ki
Kim, Hee Cheol
Cho, Yong Beom
Yun, Seong Hyeon
Lee, Woo Yong
author_facet Cho, Won Kyung
Choi, Doo Ho
Park, Hee Chul
Park, Won
Yu, Jeong Il
Park, Young Suk
Park, Joon Oh
Lim, Ho Yeong
Kang, Won Ki
Kim, Hee Cheol
Cho, Yong Beom
Yun, Seong Hyeon
Lee, Woo Yong
author_sort Cho, Won Kyung
collection PubMed
description This study investigated the prognostic impact of serum carcinoembryonic antigen (CEA) level in recurrent rectal cancer. We reviewed 745 patients who developed recurrence after curative treatment for rectal cancer between January 2000 and December 2012. Multivariate analyses for survival revealed that age > 60 years (p = 0.005), r-CEA ≥ 5 ng/ml (p < 0.001), disease free interval (DFI) < 12 months (p < 0.001), and palliative or conservative treatment (p < 0.001) were unfavorable factors.
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spelling pubmed-57396912017-12-28 Elevated CEA is associated with worse survival in recurrent rectal cancer Cho, Won Kyung Choi, Doo Ho Park, Hee Chul Park, Won Yu, Jeong Il Park, Young Suk Park, Joon Oh Lim, Ho Yeong Kang, Won Ki Kim, Hee Cheol Cho, Yong Beom Yun, Seong Hyeon Lee, Woo Yong Oncotarget Research Paper This study investigated the prognostic impact of serum carcinoembryonic antigen (CEA) level in recurrent rectal cancer. We reviewed 745 patients who developed recurrence after curative treatment for rectal cancer between January 2000 and December 2012. Multivariate analyses for survival revealed that age > 60 years (p = 0.005), r-CEA ≥ 5 ng/ml (p < 0.001), disease free interval (DFI) < 12 months (p < 0.001), and palliative or conservative treatment (p < 0.001) were unfavorable factors. Impact Journals LLC 2017-11-18 /pmc/articles/PMC5739691/ /pubmed/29285304 http://dx.doi.org/10.18632/oncotarget.22511 Text en Copyright: © 2017 Cho et al. http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Research Paper
Cho, Won Kyung
Choi, Doo Ho
Park, Hee Chul
Park, Won
Yu, Jeong Il
Park, Young Suk
Park, Joon Oh
Lim, Ho Yeong
Kang, Won Ki
Kim, Hee Cheol
Cho, Yong Beom
Yun, Seong Hyeon
Lee, Woo Yong
Elevated CEA is associated with worse survival in recurrent rectal cancer
title Elevated CEA is associated with worse survival in recurrent rectal cancer
title_full Elevated CEA is associated with worse survival in recurrent rectal cancer
title_fullStr Elevated CEA is associated with worse survival in recurrent rectal cancer
title_full_unstemmed Elevated CEA is associated with worse survival in recurrent rectal cancer
title_short Elevated CEA is associated with worse survival in recurrent rectal cancer
title_sort elevated cea is associated with worse survival in recurrent rectal cancer
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739691/
https://www.ncbi.nlm.nih.gov/pubmed/29285304
http://dx.doi.org/10.18632/oncotarget.22511
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