FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice

FAM3C, a member of FAM3 gene family, has been shown to improve insulin resistance and hyperglycemia in obese mice. This study further determined whether FAM3C functions as a hepatokine to suppress hepatic gluconeogenesis of type 1 diabetic mice. In STZ-induced type 1 diabetic mouse liver, the FAM3C-...

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Detalles Bibliográficos
Autores principales: Chen, Zhenzhen, Wang, Junpei, Yang, Weili, Chen, Ji, Meng, Yuhong, Feng, Biaoqi, Chi, Yujing, Geng, Bin, Zhou, Yong, Cui, Qinghua, Yang, Jichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739700/
https://www.ncbi.nlm.nih.gov/pubmed/29285313
http://dx.doi.org/10.18632/oncotarget.22524

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