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Impact of socioeconomic status on survival of colorectal cancer patients

Socioeconomic status (SES) has an impact on the survival of various cancers, but it has not been fully understood in colorectal cancer (CRC). The Surveillance, Epidemiology and End Results database was adopted to detect the role of SES in the survival outcomes of CRC. A total of 184,322 eligible pat...

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Autores principales: Zhang, Qian, Wang, Yufu, Hu, Hanqing, Huang, Rui, Xie, Lei, Liu, Enrui, Chen, Ying-Gang, Wang, Guiyu, Wang, Xishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739706/
https://www.ncbi.nlm.nih.gov/pubmed/29285319
http://dx.doi.org/10.18632/oncotarget.20859
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author Zhang, Qian
Wang, Yufu
Hu, Hanqing
Huang, Rui
Xie, Lei
Liu, Enrui
Chen, Ying-Gang
Wang, Guiyu
Wang, Xishan
author_facet Zhang, Qian
Wang, Yufu
Hu, Hanqing
Huang, Rui
Xie, Lei
Liu, Enrui
Chen, Ying-Gang
Wang, Guiyu
Wang, Xishan
author_sort Zhang, Qian
collection PubMed
description Socioeconomic status (SES) has an impact on the survival of various cancers, but it has not been fully understood in colorectal cancer (CRC). The Surveillance, Epidemiology and End Results database was adopted to detect the role of SES in the survival outcomes of CRC. A total of 184,322 eligible patients were included and SES status was analyzed. The multivariable analysis showed that Non-Hispanic Black (HR, 1.20; 95% CI, 1.15–1.24), being widowed (HR, 1.04; 95% CI, 1.01–1.07), any Medicaid (HR, 1.36; 95% CI, 1.33–1.39) and the lowest education level group patients had relative poorer prognosis. Besides, sex, tumor location, age, differentiation level and American Joint Committee on Cancer stage also had significant effects on overall survival of CRC. The individuals were further divided into five groups according to the number of survival-adverse factors. All of the four groups containing adverse factors showed impaired survival outcomes compared with the group containing no adverse factor.
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spelling pubmed-57397062017-12-28 Impact of socioeconomic status on survival of colorectal cancer patients Zhang, Qian Wang, Yufu Hu, Hanqing Huang, Rui Xie, Lei Liu, Enrui Chen, Ying-Gang Wang, Guiyu Wang, Xishan Oncotarget Clinical Research Paper Socioeconomic status (SES) has an impact on the survival of various cancers, but it has not been fully understood in colorectal cancer (CRC). The Surveillance, Epidemiology and End Results database was adopted to detect the role of SES in the survival outcomes of CRC. A total of 184,322 eligible patients were included and SES status was analyzed. The multivariable analysis showed that Non-Hispanic Black (HR, 1.20; 95% CI, 1.15–1.24), being widowed (HR, 1.04; 95% CI, 1.01–1.07), any Medicaid (HR, 1.36; 95% CI, 1.33–1.39) and the lowest education level group patients had relative poorer prognosis. Besides, sex, tumor location, age, differentiation level and American Joint Committee on Cancer stage also had significant effects on overall survival of CRC. The individuals were further divided into five groups according to the number of survival-adverse factors. All of the four groups containing adverse factors showed impaired survival outcomes compared with the group containing no adverse factor. Impact Journals LLC 2017-09-13 /pmc/articles/PMC5739706/ /pubmed/29285319 http://dx.doi.org/10.18632/oncotarget.20859 Text en Copyright: © 2017 Zhang et al. http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Clinical Research Paper
Zhang, Qian
Wang, Yufu
Hu, Hanqing
Huang, Rui
Xie, Lei
Liu, Enrui
Chen, Ying-Gang
Wang, Guiyu
Wang, Xishan
Impact of socioeconomic status on survival of colorectal cancer patients
title Impact of socioeconomic status on survival of colorectal cancer patients
title_full Impact of socioeconomic status on survival of colorectal cancer patients
title_fullStr Impact of socioeconomic status on survival of colorectal cancer patients
title_full_unstemmed Impact of socioeconomic status on survival of colorectal cancer patients
title_short Impact of socioeconomic status on survival of colorectal cancer patients
title_sort impact of socioeconomic status on survival of colorectal cancer patients
topic Clinical Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739706/
https://www.ncbi.nlm.nih.gov/pubmed/29285319
http://dx.doi.org/10.18632/oncotarget.20859
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