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Impact of socioeconomic status on survival of colorectal cancer patients
Socioeconomic status (SES) has an impact on the survival of various cancers, but it has not been fully understood in colorectal cancer (CRC). The Surveillance, Epidemiology and End Results database was adopted to detect the role of SES in the survival outcomes of CRC. A total of 184,322 eligible pat...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739706/ https://www.ncbi.nlm.nih.gov/pubmed/29285319 http://dx.doi.org/10.18632/oncotarget.20859 |
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author | Zhang, Qian Wang, Yufu Hu, Hanqing Huang, Rui Xie, Lei Liu, Enrui Chen, Ying-Gang Wang, Guiyu Wang, Xishan |
author_facet | Zhang, Qian Wang, Yufu Hu, Hanqing Huang, Rui Xie, Lei Liu, Enrui Chen, Ying-Gang Wang, Guiyu Wang, Xishan |
author_sort | Zhang, Qian |
collection | PubMed |
description | Socioeconomic status (SES) has an impact on the survival of various cancers, but it has not been fully understood in colorectal cancer (CRC). The Surveillance, Epidemiology and End Results database was adopted to detect the role of SES in the survival outcomes of CRC. A total of 184,322 eligible patients were included and SES status was analyzed. The multivariable analysis showed that Non-Hispanic Black (HR, 1.20; 95% CI, 1.15–1.24), being widowed (HR, 1.04; 95% CI, 1.01–1.07), any Medicaid (HR, 1.36; 95% CI, 1.33–1.39) and the lowest education level group patients had relative poorer prognosis. Besides, sex, tumor location, age, differentiation level and American Joint Committee on Cancer stage also had significant effects on overall survival of CRC. The individuals were further divided into five groups according to the number of survival-adverse factors. All of the four groups containing adverse factors showed impaired survival outcomes compared with the group containing no adverse factor. |
format | Online Article Text |
id | pubmed-5739706 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Impact Journals LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-57397062017-12-28 Impact of socioeconomic status on survival of colorectal cancer patients Zhang, Qian Wang, Yufu Hu, Hanqing Huang, Rui Xie, Lei Liu, Enrui Chen, Ying-Gang Wang, Guiyu Wang, Xishan Oncotarget Clinical Research Paper Socioeconomic status (SES) has an impact on the survival of various cancers, but it has not been fully understood in colorectal cancer (CRC). The Surveillance, Epidemiology and End Results database was adopted to detect the role of SES in the survival outcomes of CRC. A total of 184,322 eligible patients were included and SES status was analyzed. The multivariable analysis showed that Non-Hispanic Black (HR, 1.20; 95% CI, 1.15–1.24), being widowed (HR, 1.04; 95% CI, 1.01–1.07), any Medicaid (HR, 1.36; 95% CI, 1.33–1.39) and the lowest education level group patients had relative poorer prognosis. Besides, sex, tumor location, age, differentiation level and American Joint Committee on Cancer stage also had significant effects on overall survival of CRC. The individuals were further divided into five groups according to the number of survival-adverse factors. All of the four groups containing adverse factors showed impaired survival outcomes compared with the group containing no adverse factor. Impact Journals LLC 2017-09-13 /pmc/articles/PMC5739706/ /pubmed/29285319 http://dx.doi.org/10.18632/oncotarget.20859 Text en Copyright: © 2017 Zhang et al. http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Clinical Research Paper Zhang, Qian Wang, Yufu Hu, Hanqing Huang, Rui Xie, Lei Liu, Enrui Chen, Ying-Gang Wang, Guiyu Wang, Xishan Impact of socioeconomic status on survival of colorectal cancer patients |
title | Impact of socioeconomic status on survival of colorectal cancer patients |
title_full | Impact of socioeconomic status on survival of colorectal cancer patients |
title_fullStr | Impact of socioeconomic status on survival of colorectal cancer patients |
title_full_unstemmed | Impact of socioeconomic status on survival of colorectal cancer patients |
title_short | Impact of socioeconomic status on survival of colorectal cancer patients |
title_sort | impact of socioeconomic status on survival of colorectal cancer patients |
topic | Clinical Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739706/ https://www.ncbi.nlm.nih.gov/pubmed/29285319 http://dx.doi.org/10.18632/oncotarget.20859 |
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