Dnmt3b knock-down in enteric precursors reveals a possible mechanism by which this de novo methyltransferase is involved in the enteric nervous system development and the onset of Hirschsprung disease

Hirschsprung disease (HSCR, OMIM 142623) is a pathology that shows a lack of enteric ganglia along of the distal gastrointestinal tract. This aganglionosis is attributed to an abnormal proliferation, migration, differentiation and/or survival of enteric precursor cells (EPCs) derived from neural cre...

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Detalles Bibliográficos
Autores principales: Torroglosa, Ana, Villalba-Benito, Leticia, Fernández, Raquel María, Moya-Jiménez, María José, Antiñolo, Guillermo, Borrego, Salud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739746/
https://www.ncbi.nlm.nih.gov/pubmed/29290961
http://dx.doi.org/10.18632/oncotarget.22473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739746/
https://www.ncbi.nlm.nih.gov/pubmed/29290961
http://dx.doi.org/10.18632/oncotarget.22473

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