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Tetratricopeptide repeat domain 3 overexpression tends to form aggregates and inhibit ubiquitination and degradation of DNA polymerase γ

Tetratricopeptide repeat (TPR) domain 3 (TTC3) is a protein that contains canonical RING finger and TPR motifs. It is encoded by the TTC3 gene located in the Down syndrome critical region (DSCR). In this study, we used a yeast two-hybrid assay to identify several proteins that physically interact wi...

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Detalles Bibliográficos
Autores principales:	Gong, Yueqing, Wang, Xiaolan, Shang, Xuan, Xiao, Sheng Ping, Li, Wanjie, Shang, Yu, Dou, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739749/ https://www.ncbi.nlm.nih.gov/pubmed/29290964 http://dx.doi.org/10.18632/oncotarget.22476

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