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Estrogen metabolism in the human lung: impact of tumorigenesis, smoke, sex and race/ethnicity

Previous data from this group demonstrate that the murine lung metabolizes estrogen. Production of the putative carcinogen 4-hydroxyestrogen (4-OHE) is elevated within the lungs of female vs. male mice and accelerated by tobacco smoke. The goal of this study was to determine if the human lung metabo...

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Detalles Bibliográficos
Autores principales: Peng, Jing, Meireles, Sibele I., Xu, Xia, Smith, William E., Slifker, Michael J., Riel, Stacy L., Zhai, Shumenghui, Zhang, Guo, Ma, Xiang, Kurzer, Mindy S., Ma, Grace X., Clapper, Margie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739773/
https://www.ncbi.nlm.nih.gov/pubmed/29290988
http://dx.doi.org/10.18632/oncotarget.22269