Early and late effects of pharmacological ALK inhibition on the neuroblastoma transcriptome

BACKGROUND: Neuroblastoma is an aggressive childhood malignancy of the sympathetic nervous system. Despite multi-modal therapy, survival of high-risk patients remains disappointingly low, underscoring the need for novel treatment strategies. The discovery of ALK activating mutations opened the way t...

Descripción completa

Detalles Bibliográficos
Autores principales: Claeys, Shana, Denecker, Geertrui, Cannoodt, Robrecht, Kumps, Candy, Durinck, Kaat, Speleman, Frank, De Preter, Katleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739776/
https://www.ncbi.nlm.nih.gov/pubmed/29290991
http://dx.doi.org/10.18632/oncotarget.22423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739776/
https://www.ncbi.nlm.nih.gov/pubmed/29290991
http://dx.doi.org/10.18632/oncotarget.22423

Ejemplares similares