Cargando…

The role of talin2 in breast cancer tumorigenesis and metastasis

Recent studies show that talin2 has a higher affinity to β-integrin tails and is indispensable for traction force generation and cell invasion. However, its roles in cell migration, cancer cell metastasis and tumorigenesis remain to be determined. Here, we used MDA-MB-231 human breast cancer cells a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Liqing, Li, Xiang, Qi, Lei, Rychahou, Piotr, Jafari, Naser, Huang, Cai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739781/ https://www.ncbi.nlm.nih.gov/pubmed/29290996 http://dx.doi.org/10.18632/oncotarget.22449

Ejemplares similares

The molecular basis of talin2’s high affinity toward β1-integrin
por: Yuan, Yaxia, et al.
Publicado: (2017)

Loss of PHLPP expression in colon cancer: Role in proliferation and tumorigenesis
por: Liu, Jianyu, et al.
Publicado: (2008)

Talin2 regulates breast cancer cell migration and invasion by apoptosis
por: Liang, Yingfan, et al.
Publicado: (2018)

BCKDK regulates breast cancer cell adhesion and tumor metastasis by inhibiting TRIM21 ubiquitinate talin1
por: Xu, Chunlan, et al.
Publicado: (2023)

Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition
por: Xiong, Gaofeng, et al.
Publicado: (2014)

Inward Tension of Talin and Integrin-related Osmotic Pressure are involved Synergetically in the Invasion and Metastasis of Non-small Cell Lung Cancer
por: Song, Ying, et al.
Publicado: (2020)

High Stoichiometry Phosphorylation of Talin at T144/T150 or S446 Produces Contrasting Effects on Calpain-mediated Talin Cleavage and Cell Migration
por: Li, Youjun, et al.
Publicado: (2016)

Talin Phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitination and cell migration
por: Huang, Cai, et al.
Publicado: (2009)

A role for talin in presynaptic function
por: Morgan, Jennifer R., et al.
Publicado: (2004)

STK39 promotes breast cancer invasion and metastasis by increasing SNAI1 activity upon phosphorylation
por: Qiu, Zhaoping, et al.
Publicado: (2021)

Critical role of DEK and its regulation in tumorigenesis and metastasis of hepatocellular carcinoma
por: Yu, Le, et al.
Publicado: (2016)

Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation
por: Yao, Mingxi, et al.
Publicado: (2014)

LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex
por: Zacharchenko, Thomas, et al.
Publicado: (2016)

Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells
por: Zhou, Fuling, et al.
Publicado: (2016)

Talin for presynaptic endocytosis
por: LeBrasseur, Nicole
Publicado: (2004)

Talin at myotendinous junctions
Publicado: (1986)

Talin’s invasive side
por: Short, Ben
Publicado: (2014)

The mechanical response of talin
por: Yao, Mingxi, et al.
Publicado: (2016)

Expression of Talin-1 in endometriosis and its possible role in pathogenesis
por: Tang, Xian, et al.
Publicado: (2021)

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway
por: Li, Xiaoyan, et al.
Publicado: (2014)

Allosteric activation of vinculin by talin
por: Franz, Florian, et al.
Publicado: (2023)

Talin1 phosphorylation activates β1 integrins: a novel mechanism to promote prostate cancer bone metastasis
por: Jin, Jung-Kang, et al.
Publicado: (2014)

Mechanical stability of talin rod controls cell migration and substrate sensing
por: Rahikainen, Rolle, et al.
Publicado: (2017)

Chlamydial virulence factor TarP mimics talin to disrupt the talin‐vinculin complex
por: Whitewood, Austin J., et al.
Publicado: (2018)

Talin is a substrate for SUMOylation in migrating cancer cells
por: Huang, Zhiyao, et al.
Publicado: (2018)

ConFERMing the role of talin in integrin activation and mechanosignaling
por: Bachmann, Michael, et al.
Publicado: (2023)

NTF4 plays a dual role in breast cancer in mammary tumorigenesis and metastatic progression
por: Sun, Ran, et al.
Publicado: (2023)

MiR-519d suppresses breast cancer tumorigenesis and metastasis via targeting MMP3
por: Chu, Chengling, et al.
Publicado: (2018)

Functional studies of the domains of talin
Publicado: (1990)

Talin-1 interaction network promotes hepatocellular carcinoma progression
por: Chen, Peng, et al.
Publicado: (2017)

Plakoglobin: Role in Tumorigenesis and Metastasis
por: Aktary, Zackie, et al.
Publicado: (2012)

Talin1 Has Unique Expression versus Talin 2 in the Heart and Modifies the Hypertrophic Response to Pressure Overload
por: Manso, Ana Maria, et al.
Publicado: (2013)

Talin regulates moesin–NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis
por: Beaty, Brian T., et al.
Publicado: (2014)

Notch3 Maintains Luminal Phenotype and Suppresses Tumorigenesis and Metastasis of Breast Cancer via Trans-Activating Estrogen Receptor-α
por: Dou, Xiao-Wei, et al.
Publicado: (2017)

Role of AMPK and Akt in triple negative breast cancer lung colonization
por: Johnson, Jeremy, et al.
Publicado: (2021)

The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer
por: Wang, Zhongyuan, et al.
Publicado: (2021)

Talin is cut out for intercellular adhesion
por: Short, Ben
Publicado: (2012)

Talin gives integrins a nudge
por: Leslie, Mitch
Publicado: (2012)

Talin as a mechanosensitive signaling hub
por: Goult, Benjamin T., et al.
Publicado: (2018)

Talin: a protein designed for mechanotransduction
por: Burridge, Keith
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1bpngehlmo6hs8odfi1asf222r