Targeting G-protein coupled receptor-related signaling pathway in a murine xenograft model of appendiceal pseudomyxoma peritonei

Cancer cells aberrantly express mucins to enhance their survival. Relative chemoresistance of appendiceal pseudomyxoma peritonei (PMP) is attributed to abundant extracellular mucin 2 (MUC2) protein production. We hypothesized that simultaneous MUC2 inhibition and apoptosis induction would be effecti...

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Detalles Bibliográficos
Autores principales: Dilly, Ashok K., Honick, Brendon D., Lee, Yong J., Guo, Zong S., Zeh, Herbert J., Bartlett, David L., Choudry, Haroon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739782/
https://www.ncbi.nlm.nih.gov/pubmed/29290997
http://dx.doi.org/10.18632/oncotarget.22455

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