Transferrin receptor 1 upregulation in primary tumor and downregulation in benign kidney is associated with progression and mortality in renal cell carcinoma patients

The central dysregulated pathway of clear cell (cc) renal cell carcinoma (RCC), the von Hippel Lindau/hypoxia inducible factor-α axis, is a key regulator of intracellular iron levels, however the role of iron uptake in human RCC tumorigenesis and progression remains unknown. We conducted a thorough,...

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Detalles Bibliográficos
Autores principales: Greene, Christopher J., Attwood, Kristopher, Sharma, Nitika J., Gross, Kenneth W., Smith, Gary J., Xu, Bo, Kauffman, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739796/
https://www.ncbi.nlm.nih.gov/pubmed/29291011
http://dx.doi.org/10.18632/oncotarget.22323

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