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Protease-activated receptor-1 (PAR-1): a promising molecular target for cancer

PAR-1 is expressed not only in epithelium, neurons, astrocytes, immune cells, but also in cancer-associated fibroblasts, ECs (epithelial cells), myocytes of blood vessels, mast cells, and macrophages in tumor microenvironment, whereas PAR-1 stimulates macrophages to synthesize and secrete thrombin a...

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Detalles Bibliográficos
Autores principales:	Liu, Xuan, Yu, Jiahui, Song, Shangjin, Yue, Xiaoqiang, Li, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739818/ https://www.ncbi.nlm.nih.gov/pubmed/29291033 http://dx.doi.org/10.18632/oncotarget.21015

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