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Deep sequencing of blood and gut T-cell receptor β-chains reveals gluten-induced immune signatures in celiac disease

Celiac disease (CD) patients mount an abnormal immune response to gluten. T-cell receptor (TCR) repertoires directed to some immunodominant gluten peptides have previously been described, but the global immune response to in vivo gluten exposure in CD has not been systematically investigated yet. He...

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Detalles Bibliográficos
Autores principales: Yohannes, Dawit A., Freitag, Tobias L., de Kauwe, Andrea, Kaukinen, Katri, Kurppa, Kalle, Wacklin, Pirjo, Mäki, Markku, Arstila, T. Petteri, Anderson, Robert P., Greco, Dario, Saavalainen, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740085/
https://www.ncbi.nlm.nih.gov/pubmed/29269859
http://dx.doi.org/10.1038/s41598-017-18137-9