Cargando…

Deep sequencing of blood and gut T-cell receptor β-chains reveals gluten-induced immune signatures in celiac disease

Celiac disease (CD) patients mount an abnormal immune response to gluten. T-cell receptor (TCR) repertoires directed to some immunodominant gluten peptides have previously been described, but the global immune response to in vivo gluten exposure in CD has not been systematically investigated yet. He...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yohannes, Dawit A., Freitag, Tobias L., de Kauwe, Andrea, Kaukinen, Katri, Kurppa, Kalle, Wacklin, Pirjo, Mäki, Markku, Arstila, T. Petteri, Anderson, Robert P., Greco, Dario, Saavalainen, Päivi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740085/ https://www.ncbi.nlm.nih.gov/pubmed/29269859 http://dx.doi.org/10.1038/s41598-017-18137-9

Ejemplares similares

Effects of In Vivo Gluten Challenge on PBMC Gene Expression Profiles in Diet Treated Celiac Disease
por: Yohannes, Dawit A., et al.
Publicado: (2020)

Clustering based approach for population level identification of condition-associated T-cell receptor β-chain CDR3 sequences
por: Yohannes, Dawit A., et al.
Publicado: (2021)

Dissecting the contribution of single nucleotide polymorphisms in CCR9 and CCL25 genomic regions to the celiac disease phenotype
por: Airaksinen, Laura, et al.
Publicado: (2021)

Gastrointestinal Symptoms in Celiac Disease Patients on a Long-Term Gluten-Free Diet
por: Laurikka, Pilvi, et al.
Publicado: (2016)

Differences Between Familial and Sporadic Celiac Disease
por: Airaksinen, Laura, et al.
Publicado: (2020)

First-degree Relatives of Celiac Disease Patients Have Increased Seroreactivity to Serum Microbial Markers
por: Viitasalo, Liisa, et al.
Publicado: (2020)

Influence of HLA-DQ2.5 Dose on Clinical Picture of Unrelated Celiac Disease Patients
por: Airaksinen, Laura, et al.
Publicado: (2020)

The Long-Term Consumption of Oats in Celiac Disease Patients Is Safe: A Large Cross-Sectional Study
por: Aaltonen, Katri, et al.
Publicado: (2017)

The Phenotype of Celiac Disease Has Low Concordance between Siblings, Despite a Similar Distribution of HLA Haplotypes
por: Kauma, Saana, et al.
Publicado: (2019)

Prevalence of vomiting and nausea and associated factors after chronic and acute gluten exposure in celiac disease
por: Ahonen, Iida, et al.
Publicado: (2023)

Validation of the X-ray microtomography in the assessment of duodenal morphometry and surface area in celiac disease
por: Virta, Johannes, et al.
Publicado: (2022)

Type 1 and type 2 diabetes in celiac disease: prevalence and effect on clinical and histological presentation
por: Kylökäs, Antti, et al.
Publicado: (2016)

Non-Biopsy Serology-Based Diagnosis of Celiac Disease in Adults Is Accurate with Different Commercial Kits and Pre-Test Probabilities
por: Ylönen, Venla, et al.
Publicado: (2020)

Coeliac disease re‐screening among once seronegative at‐risk relatives: A long‐term follow‐up study
por: Paavola, Saana, et al.
Publicado: (2022)

Factors associated with growth disturbance at celiac disease diagnosis in children: A retrospective cohort study
por: Nurminen, Samuli, et al.
Publicado: (2015)

Coexisting Type 1 Diabetes, Persistent Symptoms, and Financial Issues Associate With Poorer Adherence to a Gluten-Free Diet in Celiac Disease After Transition From Pediatrics to Adult Care
por: Kivelä, Laura, et al.
Publicado: (2022)

Small- bowel mucosal changes and antibody responses after low- and moderate-dose gluten challenge in celiac disease
por: Lähdeaho, Marja-Leena, et al.
Publicado: (2011)

Validation of Morphometric Analyses of Small-Intestinal Biopsy Readouts in Celiac Disease
por: Taavela, Juha, et al.
Publicado: (2013)

Clinical benefit of gluten-free diet in screen-detected older celiac disease patients
por: Vilppula, Anitta, et al.
Publicado: (2011)

Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits
por: Stenman, Satumarja M, et al.
Publicado: (2008)

Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes
por: Cerqueira, Juliana X. M., et al.
Publicado: (2021)

Small-intestinal TG2-specific plasma cells at different stages of coeliac disease
por: Hietikko, Minna, et al.
Publicado: (2018)

A B-Cell Gene Signature Correlates With the Extent of Gluten-Induced Intestinal Injury in Celiac Disease
por: Garber, Mitchell E., et al.
Publicado: (2017)

Iron Transporter Protein Expressions in Children with Celiac Disease
por: Repo, Marleena, et al.
Publicado: (2021)

Daily Life Restrictions are Common and Associated with Health Concerns and Dietary Challenges in Adult Celiac Disease Patients Diagnosed in Childhood
por: Leinonen, Heini, et al.
Publicado: (2019)

X-ray microtomography is a novel method for accurate evaluation of small-bowel mucosal morphology and surface area
por: Virta, Johannes, et al.
Publicado: (2020)

Predictors of persistent symptoms and reduced quality of life in treated coeliac disease patients: a large cross-sectional study
por: Paarlahti, Pilvi, et al.
Publicado: (2013)

Long-Term Consumption of Oats in Adult Celiac Disease Patients
por: Kaukinen, Katri, et al.
Publicado: (2013)

Association of concomitant autoimmunity with the disease features and long-term treatment and health outcomes in Celiac disease
por: Tauschi, Riku, et al.
Publicado: (2022)

Gluten-Induced Extra-Intestinal Manifestations in Potential Celiac Disease—Celiac Trait
por: Popp, Alina, et al.
Publicado: (2019)

Use of health care services and pharmaceutical agents in coeliac disease: a prospective nationwide study
por: Ukkola, Anniina, et al.
Publicado: (2012)

Intestinal TG3- and TG2-Specific Plasma Cell Responses in Dermatitis Herpetiformis Patients Undergoing a Gluten Challenge
por: Sankari, Hanna, et al.
Publicado: (2020)

Review article: Systemic consequences of coeliac disease
por: Laurikka, Pilvi, et al.
Publicado: (2022)

Thioredoxin Is Involved in Endothelial Cell Extracellular Transglutaminase 2 Activation Mediated by Celiac Disease Patient IgA
por: Antonella Nadalutti, Cristina, et al.
Publicado: (2013)

IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease
por: Einarsdottir, Elisabet, et al.
Publicado: (2009)

Increasing prevalence and high incidence of celiac disease in elderly people: A population-based study
por: Vilppula, Anitta, et al.
Publicado: (2009)

Significance of low ferritin without anaemia in screen‐detected, adult coeliac disease patients
por: Repo, Marleena, et al.
Publicado: (2022)

Gluten-free diet adherence in children with screening-detected celiac disease using a prospective birth cohort study
por: Mehta, Pooja, et al.
Publicado: (2023)

Persistent symptoms are diverse and associated with health concerns and impaired quality of life in patients with paediatric coeliac disease diagnosis after transition to adulthood
por: Vuolle, Satu, et al.
Publicado: (2022)

Celiac disease and non-celiac gluten sensitivity
por: Lebwohl, Benjamin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_l400jqfu197uu52248kr3a8qnv