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Liver decompensation predicts ribavirin overexposure in hepatitis C virus patients treated with direct-acting antivirals

AIM: To determine whether ribavirin (RBV) concentrations differ according to cirrhosis stage among cirrhotic patients treated with interferon-free regimens. METHODS: We included patients with hepatitis C virus and cirrhosis [Child-Pugh (CP) A or B], Glomerular Filtration Rate ≥ 60 mL/min, who starte...

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Detalles Bibliográficos
Autores principales: Guardigni, Viola, Badia, Lorenzo, Conti, Matteo, Rinaldi, Matteo, Mancini, Rita, Viale, Pierluigi, Verucchi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740096/
https://www.ncbi.nlm.nih.gov/pubmed/29290908
http://dx.doi.org/10.4254/wjh.v9.i34.1270