The podoplanin-CLEC-2 axis inhibits inflammation in sepsis

Platelets play a critical role in vascular inflammation through the podoplanin and collagen/fibrin receptors, C-type-lectin-like-2 (CLEC-2) and glycoprotein VI (GPVI), respectively. Both receptors regulate endothelial permeability and prevent peri-vascular bleeding in inflammation. Here we show that...

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Detalles Bibliográficos
Autores principales: Rayes, Julie, Lax, Siân, Wichaiyo, Surasak, Watson, Stephanie K., Di, Ying, Lombard, Stephanie, Grygielska, Beata, Smith, Stuart W., Skordilis, Kassiani, Watson, Steve P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740111/
https://www.ncbi.nlm.nih.gov/pubmed/29269852
http://dx.doi.org/10.1038/s41467-017-02402-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740111/
https://www.ncbi.nlm.nih.gov/pubmed/29269852
http://dx.doi.org/10.1038/s41467-017-02402-6

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