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Thromboembolic and neurologic sequelae of discontinuation of an antihyperlipidemic drug during ongoing warfarin therapy

Warfarin and antihyperlipidemics are commonly co-prescribed. Some antihyperlipidemics may inhibit warfarin deactivation via the hepatic cytochrome P450 system. Therefore, antihyperlipidemic discontinuation has been hypothesized to result in underanticoagulation, as warfarin metabolism is no longer i...

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Detalles Bibliográficos
Autores principales: Leonard, Charles E., Brensinger, Colleen M., Bilker, Warren B., Kimmel, Stephen E., Whitaker, Heather J., Hennessy, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740131/
https://www.ncbi.nlm.nih.gov/pubmed/29269848
http://dx.doi.org/10.1038/s41598-017-18318-6