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Promoter-enhancer interactions identified from Hi-C data using probabilistic models and hierarchical topological domains
Proximity-ligation methods such as Hi-C allow us to map physical DNA–DNA interactions along the genome, and reveal its organization into topologically associating domains (TADs). As the Hi-C data accumulate, computational methods were developed for identifying domain borders in multiple cell types a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740158/ https://www.ncbi.nlm.nih.gov/pubmed/29269730 http://dx.doi.org/10.1038/s41467-017-02386-3 |