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Minimizing carry-over PCR contamination in expanded CAG/CTG repeat instability applications

Expanded CAG/CTG repeats underlie the aetiology of 14 neurological and neuromuscular disorders. The size of the repeat tract determines in large part the severity of these disorders with longer tracts causing more severe phenotypes. Expanded CAG/CTG repeats are also unstable in somatic tissues, whic...

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Detalles Bibliográficos
Autores principales:	Aeschbach, Lorène, Dion, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740160/ https://www.ncbi.nlm.nih.gov/pubmed/29269788 http://dx.doi.org/10.1038/s41598-017-18168-2

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