Induced Bias Due to Crossover Within Randomized Controlled Trials in Surgical Oncology: A Meta-regression Analysis of Minimally Invasive versus Open Surgery for the Treatment of Gastrointestinal Cancer

BACKGROUND: Randomized controlled trials (RCTs) inform clinical practice and have provided the evidence base for introducing minimally invasive surgery (MIS) in surgical oncology. Crossover (unplanned intraoperative conversion of MIS to open surgery) may affect clinical outcomes and the effect size...

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Detalles Bibliográficos
Autores principales: Garas, George, Markar, Sheraz R., Malietzis, George, Ashrafian, Hutan, Hanna, George B., Zacharakis, Emmanouil, Jiao, Long R., Argiris, Athanassios, Darzi, Ara, Athanasiou, Thanos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Gastrointestinal Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740197/
https://www.ncbi.nlm.nih.gov/pubmed/29110271
http://dx.doi.org/10.1245/s10434-017-6210-y

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