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A Retrospective Cohort Analysis Shows that Coadministration of Minocycline with Colistin in Critically Ill Patients Is Associated with Reduced Frequency of Acute Renal Failure

Nonclinical studies have suggested that oxidative damage, caspase-mediated apoptosis, and inducible nitric oxide synthase levels may be involved in the pathogenesis of colistin (CST)-associated acute renal failure. MIN inhibits caspase 1, caspase 3, and inducible nitric oxide synthase, leading to th...

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Detalles Bibliográficos
Autores principales:	Lodise, Thomas P., Fan, Weihong, Griffith, David C., Dudley, Michael N., Sulham, Katherine A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Clinical Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740356/ https://www.ncbi.nlm.nih.gov/pubmed/29038261 http://dx.doi.org/10.1128/AAC.01165-17

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