Cargando…
Combinations of Respiratory Chain Inhibitors Have Enhanced Bactericidal Activity against Mycobacterium tuberculosis
As an obligate aerobe, Mycobacterium tuberculosis uses its electron transport chain (ETC) to produce energy via oxidative phosphorylation. This pathway has recently garnered a lot of attention and is a target for several new antimycobacterials. We tested the respiratory adaptation of M. tuberculosis...
Autores principales: | Berube, Bryan J., Parish, Tanya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740367/ https://www.ncbi.nlm.nih.gov/pubmed/29061760 http://dx.doi.org/10.1128/AAC.01677-17 |
Ejemplares similares
-
Novel MenA Inhibitors Are Bactericidal against Mycobacterium tuberculosis and Synergize with Electron Transport Chain Inhibitors
por: Berube, Bryan J., et al.
Publicado: (2019) -
Inoculum-dependent bactericidal activity of a Mycobacterium tuberculosis MmpL3 inhibitor
por: Berube, Bryan, et al.
Publicado: (2023) -
Inoculum-dependent bactericidal activity of a Mycobacterium tuberculosis MmpL3 inhibitor
por: Berube, Bryan, et al.
Publicado: (2023) -
Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones
por: Basarab, Gregory S., et al.
Publicado: (2022) -
Novel Screen to Assess Bactericidal Activity of Compounds Against Non-replicating Mycobacterium abscessus
por: Berube, Bryan J., et al.
Publicado: (2018)